At 11.40 hours on 1 June 1942 the unescorted and unarmed Hampton Roads (Master William Hanson Lane) was stopped by two warning shots fired across the stern by U-106, while proceeding on a zigzag course at 6 knots northwest of Cape San Antonio, Cuba. The most men of the eight officers and 20 crewmen on board immediately began to abandon ship in the port lifeboat and a raft, while the radio operator sent distress signals. At 11.46 hours, U-106 fired one torpedo that struck the ship at the #3 hatch, causing the vessel to sink within one minute. The master, one officer and two crewmen were still on board and were lost. The second mate was in the water near the lifeboat when the torpedo struck at close range and was not seen again. The 23 survivors were picked up seven hours later by the Alcoa Pathfinder and landed at Curaçao on 6 June.