| Navy | The US Navy |
| Type | Destroyer |
| Class | Benson / Gleaves |
| Pennant | DD 422 |
| Built by | Bethlehem Shipbuilding Corp. (Quincy, Massachusetts, U.S.A.) |
| Ordered | |
| Laid down | 16 May 1938 |
| Launched | 26 Mar 1940 |
| Commissioned | 18 Sep 1940 |
| End service | 18 Mar 1946 |
| Loss position | |
| History | Decommissioned 18 March 1946. |
Commands listed for USS Mayo (DD 422)
Please note that we're still working on this section.
| Commander | From | To | ||
| 1 | Lt. Campbell Dallas Emory, USN | 18 Sep 1940 | ??? | |
| 2 | Lt.Cdr. Ralston Birto Varzant, USN | 1941 | ??? | |
| 3 | Cdr. Irving Terrill Duke, USN | ??? | ??? | |
| 4 | Cdr. Frederick Shrom Habecker, USN | ??? | ??? | |
| 5 | Cdr. Albert D. Kaplan, USN | ??? | ??? | |
| 6 | Lt.Cdr. Wayne Herkness, II, USN | ??? | ??? | |
| 7 | Lt.Cdr. Arthur Boyden Glidden, USNR | ??? | ??? | |
| 8 | Lt.Cdr. Wayne Herkness, II, USN | 1945 | 18 Mar 1946 | |
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Noteable events involving Mayo include:
25 Mar 1942
USS Mayo picks up 4 survivors from the Dutch tanker Ocana that was torpedoed and sunk south of Nova Scotia, Canada in position 42º36'N, 65º30'W by the German submarine U-552.
11 Jul 1942
USS Livermore and USS Mayo together pick up 32 survivors from the American merchant Santa Rita that was torpedoed and sunk on 9 July 1942 by the German submarine U-172 about 700 nautical miles north-east of Puerto Rico in position 26º11'N, 55º40'W.