8 Dec, 1941
After the attack on Pearl Harbour USS Pike (Lt.Cdr. W.A. New) left Manila for her first war patrol. She was to guard the shipping lanes between Manila and Hong Kong. Late December she returned to base.

31 Dec, 1941
USS Pike (Lt.Cdr. W.A. New) left Manila for her second war patrol.

24 Jan, 1942
USS Pike (Lt.Cdr. W.A. New) ended her second war patrol at Darwin, Australia.

5 Feb, 1942
USS Pike (Lt.Cdr. W.A. New) left Darwin for her third war patrol.

28 Mar, 1942
USS Pike (Lt.Cdr. W.A. New) ends her third war patrol when she returnes to base at Fremantle, Australia.

19 Apr, 1942
USS Pike (Lt.Cdr. W.A. New) leaves Fremantle for her 4th war patrol. She was to patrol north of the Palau Islands and off Wake Island.

25 May, 1942
USS Pike (Lt.Cdr. W.A. New) ended her 4th war patrol when she returned to base at Pearl Harbour.

30 May, 1942
USS Pike (Lt.Cdr. W.A. New) leaves Pearl Harbour for her 5th war patrol. She was ordered to patrol north of Oahu.

9 Jun, 1942
USS Pike (Lt.Cdr. W.A. New) ended her 5th war patrol when she returned to Pearl Harbour. She weas sent to the Mare Island Navy Yard for an overhaul.

14 Jan, 1943
During her 5th war patrol USS Pike (Lt.Cdr. W.A. New) guided bombers to Wake Island in December 1942, but on 14 Janaury 1943 she was damaged by bombs and depth charges off Ichie Saki, southern Honshu, Japan. due to the damages she has to terminate her patrol.

31 Mar, 1943
USS Pike (Lt.Cdr. L.D. McGregor, Jr) left Pearl Harbour for her 6th war patrol. She was to patrol in the Caroline Islands area.

14 Apr, 1943
USS Pike (Lt.Cdr. L.D. McGregor, Jr) torpedoes and damages the Japanese transport ship Madras Maru (3802 GRT) north of the Admiralty Islands in position 01º25'N, 148º22'E. (see map)

25 Apr, 1943
USS Pike (Lt.Cdr. L.D. McGregor, Jr) shells Satawan Island, Caroline Islands.

22 Jul, 1943
USS Pike (Lt.Cdr. L.D. McGregor, Jr) left Pearl Harbour for her 7th and last war patrol. She was to patrol off Marcus Island.

5 Aug, 1943
USS Pike (Lt.Cdr. L.D. McGregor, Jr) torpedoes and sinks the Japanese transport ship Shoju Maru (1992 GRT) west of Marcus Island in position 24º30'N, 158º50'E. (see map)

22 Aug, 1943
USS Pike (Lt.Cdr. L.D. McGregor, Jr) torpedoes and damages the Japanese transport ship Toun Maru (1915 GRT) in the Philippine Sea in position 21º22'N, 137º50'E. (see map)

28 Sep, 1943
USS Pike left Pearl Harbour bound for New London on the U.S. east coast as she was now assigned to training duties.