| Navy | The Royal Navy |
| Type | Submarine |
| Class | O |
| Pennant | N 46 |
| Built by | William Beardmore & Co. (Dalmuir, Scotland) |
| Ordered | 21 Dec 1926 |
| Laid down | 14 Apr 1927 |
| Launched | 26 Feb 1929 |
| Commissioned | 23 Sep 1930 |
| Lost | 19 Jun 1940 |
| Loss position | 32.30N, 24.00E |
| History | HMS Orpheus (Lt.Cdr. James Anthony Surtees Wise, RN) was sunk on 19 June 1940 while on patrol about 25 nautical miles north of Tobruk, Libya in position 32º30'N, 24º00'E by the Italian destroyer Turbine. Orpheus had departed Malta on 10 June for a patrol of Syracuse. Orpheus was declared overdue on the 27th. |
Commands listed for HMS Orpheus (N 46)
Please note that we're still working on this section.
| Commander | From | To | |
| 1 | Lt.Cdr. Charles James Blake, RN | 19 Jun 1938 | Jun 1940 |
| 2 | Lt.Cdr. James Anthony Surtees Wise, RN | Jun 1940 | 19 Jun 1940 (+) |
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