| Navy | The US Navy |
| Type | Destroyer |
| Class | Fletcher |
| Pennant | DD 512 |
| Built by | Bath Iron Works (Bath, Maine, U.S.A.) |
| Ordered | 9 Sep 1940 |
| Laid down | 18 May 1942 |
| Launched | 27 Oct 1942 |
| Commissioned | 8 Jan 1943 |
| Lost | 18 Dec 1944 |
| Loss position | 14° 57'N, 127° 58'E |
| History | Foundered in a typhoon east of Samar in position 14º57'N, 127º58'E, 315 of the crew were lost including the Commanding Officer, Lt.Cdr. James Paul Andrea, USN. There were only 24 survivors, which were rescued by the USS Gatling, USS Swearer and USS Tabberer. |
Commands listed for USS Spence (DD 512)
Please note that we're still working on this section.
| Commander | From | To | |
| 1 | Lt.Cdr. Henry Jacques Armstrong, Jr., USN | 8 Jan 1943 | 8 Jul 1944 |
| 2 | James Paul Andrea, USN | 8 Jul 1944 | 18 Dec 1944 (+) |
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